Could the FDA-approved anti-HIV PR inhibitors be promising anticancer agents? An answer from enhanced docking approach and molecular dynamics analyses

Olayide A Latest Product Releases & Innovations – Stay Updated! Arodola, Mahmoud ES SolimanMolecular Modelling and Drug Design Lab, School of Health Sciences, Westville Campus, University of KwaZulu-Natal, Durban, South AfricaAbstract: Based on experimental data, the anticancer activity of nelfinavir (NFV), a US Food and Drug Administration (FDA)

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Vehicle Optimal Velocity Curves for Minimum-Time Maneuver

A problem in vehicle minimum-time read more maneuver is the assumption that a vehicle passes through a given path in a minimal amount of time without deviating from the boundary of the given path.Vehicle handling inverse dynamics provides a new perspective to solve such problem.Based on inverse dynamics, this paper transformed the problem of optima

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Clinical differential factors in patients with hereditary transthyretin amyloidosis with Val142Ile and Ser43Asn mutations

Abstract Background Hereditary transthyretin amyloidosis (hATTR) is a rare autosomal dominant disease with high clinical variability, influenced by both genotype and the geographic origins of carriers.There is a limited understanding of the Val142Ile and Ser43Asn recognised mutations in Ecuador and Colombia.Therefore, the objective of this study is

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